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Selected Publications

- Taida Huang, Yonghui Hou, Xia Wang, Liang Wang, Chenju Yi, Cuifang Wang, Xiaoyun Sun, Paul K H Tam, Sai Ming Ngai, Mai Har Sham, Alan J Burns, Wood Yee Chan (2022) Direct interaction of Sox10 with cadherin-19 mediates early sacral neural crest cell migration: implications for enteric nervous system development defects. Gastroenterology. 162(1):179-192.e11.

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- Haoran Zhang, Junjie Xie, Karl Kam Hei So, Ka Kui Tong, Jearn Jang Sae-Pang, Li Wang, Sze Lan Tsang, Wood Yee Chan, Elaine Yee Man Wong, Mai Har Sham (2021) Hoxb3 regulates Jag1 expression in pharyngeal epithelium and affects interaction with neural crest cells. Frontier in Physiology 11:612230.

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- Xia Wang, Chunman Li, Zeyao Zhu, Li Yuan, Wood Yee Chan (2020) Extracellular Matrix Remodeling During Palate Development. Organogenesis Volume 16, 2020 - Issue 2: 43-60

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- Na Shang, Juliana Tsz Yan Lee, Taida Huang, Chengdong Wang, Tin Lap Lee, Samuel C. Mok, Hui Zhao, Wood Yee Chan (2020) Disabled-2: a positive regulator of the early differentiation of myoblasts. Cell and Tissue Research (2020) 381:493–508

 

- Yunlong Chen, Yan-Fang Xian, Steven Loo, Zhengquan Lai, Wood Yee Chan, Ling Liu, Zhi-Xiu Lin (2020) Huang-Lian-Jie-Du extract ameliorates atopic dermatitis-like skin lesions induced by 2,4-dinitrobenzene in mice via suppression of MAPKs and NF-κB pathways. Journal of Ethnopharmacology 249 (2020) 112367. 

 

- Si Yun Shu, Gang Jiang, Zhaocong Zheng, Lin Ma, Bin Wang, Qiyi Zeng, Hong Li, Shen Tan, Bin Liu, Wood Yee Chan, Sheng Wu, Chunhua Zhu, Changke Li, Peng Wang, Jang-Yen Wu (2019) A New Neural Pathway from the Ventral Striatum to the Nucleus Basalis of Meynert with Functional Implication to Learning and Memory. Molecular Neurobiology (2019) 56:7222–7233

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- Jeffrey Chun-Yin Lee, Patrick Shu-Hang Yung, Mak-Ham Lam, Aaron See-Long Hung, Daniel Tik-Pui Fong, Wood Yee Chan, Kai-Ming Chan (2019) A non-invasive biomechanical device to quantify knee rotational laxity: Verification of the device in human cadaveric specimens. Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology 16 (2019) 19-23

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- Li YH, Tai WC, Khan I, Lu C, Lu Y, Wong WY, Chan WY, Hsiao WW, Lin G (2018) Toxicoproteomic assessment of liver responses to acute pyrrolizidine alkaloid intoxication in rats. Journal of Environmental Science and Health, Part C 36: 65-83.

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-  Burns AJ, Goldstein AM, Newgreen DF, Stamp L, Schafer KH, Metzger M, Hotta R, Young HM, Andrews PW, Thapar N, Belkind-Gerson J, Bondurand N, Bornstein JC, Chan WY, Cheah K, Gershon MD, Heuckerorth RO, Hofstra RMW, Just L, Kapur RP, King SK, McCann C, Nagy N, Ngan E, Obermayr F, Pachins V, Pasricha PJ, Sham MH, Tam P, Berghe PV (2016) White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies. Developmental Biology 417: 229-251.

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- Wang C, Kam RKT, Shi W, Xia Y, Chan X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Yi, Zhao Hui (2015) The proto-oncogene transcription factor Ets1 regulates neural crest development through histone deacetylase 1 to mediate output of bone morphogenetic protein signaling. Journal of Biological Chemistry 290: 21925-21938.

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- Wong CH, Ngugyen L, Peh J, Luu LM, Sanchez JS, Richardson SL, Tuccinardi T, Tsoi H, Chan WY, Chan HY, Baranger A M, Hergenrother PJ and Zimmerman SC (2014) Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor. Journal of American Chemistry Society 136: 6335-6361.

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- Kam RKT, Shi W, Chan SO, Chen Y, Xu G, Lau CBS, Fung KP, Chan WY and Zhao H (2013) Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning. Journal of Biological Chemistry 288: 31477-31487.
 

- Wang X, Chan AKK, Sham MH, Burns AJ and Chan WY (2011) Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo.  Gastroenterology 141(3): 992-1002.

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- Qu ZQ, Zhou Y, Zeng YS, Lin YK, Li Y, Zhong ZQ, Chan WY (2012) Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat. PLoS One 7(1):e29641.

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- Zeng X, Zeng Y, Ma Y, Lu L, Du B, Zhang W, Li Y and Chan WY (2011) Bone marrow mesenchymal stem cells in a three dimensional gelatine sponge scaffold attenuate inflammation, promote angiogenesis and reduce cavity formation in experimental spinal cord injury.  Cell Transplantation (in press)

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- Chan WY, Ng TB, Lam JSY, Wong JH, Chu KT, Ngai PHK, Lam SK and Wang HX (2010) The mushroom ribosome-inactivating protein lyophyllin exerts deleterious effects on mouse embryonic development in vitro.  Applied Microbiology and Biotechnology  85: 985-994.

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Chan WY, Xia CL, Yew DT, Zhao H and Mok SC (2009) Expression of Dab2, a tumor suppressor, in the human fetal hippocampus and neocortex.  Neuroembryology and Aging 5: 182-190.

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- Cheung KK, Mok SC, Rezaie P and Chan WY (2008) Dynamic expression of Dab2 in the mouse embryonic central nervous system. BMC Developmental Biology 8: 76.

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Chan WY, Kohsaka S and Rezaie P (2007) The origin and cell lineage of microglia – New concepts.  Brain Research Reviews 53: 344-354.

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- Li KKH, Sung RYT, Huang WZ, Yang M, Pong NH, Lee SM, Chan WY, Zhao H, To MY, Fok TF, Li CK, Wong YO and Ng HK (2006) Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin.  Circulation 113: 2211-2220.

 

- Cheung KK, Chan WY and Burnstock G (2005) Expression of P2X purinoceptors during rat brain development and their Inhibitory role on motor axon outgrowth in neural tube explant cultures. Neuroscience 133: 937-945.

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Chan WY, Cheung CS, Yung KM and Copp AJ (2004) Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant. Development 131: 3367-3379.

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Chan WY, Lorke DE, Tiu SC and Yew DT (2002) Proliferation and apoptosis in the developing human neocortex. Anatomical Record 267: 261-276.

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- Fan M, Mi R, Yew DT and Chan WY (2001) Analysis of gene expression following sciatic nerve crush and spinal cord hemisection in the mouse by microarray expression profiling. Cellular and Molecular Neurobiology 21: 497-508.

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- Chan WY, Cheung KK, Schorge JO, Huang LW, Welch WR, Bell DA, Berkowitz RS and Mok SC (2000) Relationship of bcl-2 and p53 protein expression, apoptosis and p53 mutation in human epithelial ovarian cancers. American Journal of Pathology 156: 409-417.

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- Yew DT and Chan WY (1999) Early appearance of acetylcholinergic, serotoninergic and peptidergic neurons and fibers in the developing human central nervous system. Microscopy Research and Technique 45: 389-400.

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- Mok SC, Chan WY, Cheung KK, Wong KK, Lau CC, Baldinin A, Colitti CV, Rock C and Berkowitz RS (1998) Doc-2, a novel putative tumor suppressor gene in human epithelial ovarian cancer. Oncogene 16: 2381-2387.

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